Department of Pharmacology

General Description

Pharmacology is a science that studies the effects of drugs, their mechanisms of action and their use in therapy. It deals with detection and development of the most suitable chemical substances for the treatment, diagnosis, prophylaxis of diseases and for other medical purposes by conducting in vitro experiments on cells, subcellular structures, bioactive molecules, tissues and organs as well as in vivo studies in animals and/or humans. It is both a discipline of medicine and pharmacy that contributes to drug development studies by examining the effects of newly synthesized or plant-derived substances in laboratory animal studies or clinical human studies. Pharmacology conducts this complex and intensive research from bench to bedside in collaboration with related disciplines and subdisciplines.

As the department of pharmacology, we aim to raise pharmacologists who aim to provide the continuity of the pharmacological effect of the drug to the patient and to ensure safety, efficacy and quality of the drug, who can solve the multifaceted problems that arise either at the individual level or at the community level, and who are responsible for maintaining the efficiency and competency of their professional knowledge througout their professional life.

Research
• Cardiovascular pharmacology
• Endothelial dysfunction
• Erectile dysfunction
• Diabetes
• Cancer

Signalling pathways which have roles in vascular pathogenesis, investigation of potential candidate drugs in the treatment of vascular and endothelial dysfunction, gasotransmitters (nitric oxide, hydrogen sulfide, and carbon monoxide), cancer progression, neoplastic transformation, apoptosis, intracellular calcium homeostasis, functional genomics, oxidative stress, antioxidant proteins, matrix metalloproteinases, telomeres, endothelium and nitric oxide are within our interests. We have been applying techiques to study erectile dysfunction, perivascular intimal thickening, atherosclerosis, balloon angioplasty, diabetes, oxidative stress, hypercholesterolemia, cardiac ischemia models as well as cell culture and posttranscriptional gene silencing techniques. The ongoing studies aims the discovery of drug candidates and secondary metabolites targeting hydrogen sulfide.

Academıc Staff
Prof. Dr. Zeliha KERRY(Head of Dep.)
Prof. Dr. Mukadder YASA
Prof. Dr. Günay YETİK ANACAK
Assoc. Prof. Dr. Gülnur SEVİN
Assoc. Prof. Dr. Saadet TÜRKSEVEN DI PASCOLI
Assoc. Prof. Dr. Yasemin ERAÇ
Assoc. Prof. Dr. Gönen ÖZŞARLAK SÖZER
Res. Assist. Dr. Çiğdem SELLİ KARAKAYA